Effects of repeated administration of d-amphetamine on Sidman avoidance responding in rats
- 1 November 1980
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 71 (1), 105-107
- https://doi.org/10.1007/bf00433263
Abstract
The effects of repeated administration of d-amphetamine (0.5 mg/kg SC) on Sidman avoidance responding in rats were investigated. The response (lever-pressing) enhancing effect of d-amphetamine increased progressively after repeated administration. The change in behavior was more marked in the animals exposed to the avoidance situation during the period of the drug effect than in those given the drug after termination of each avoidance session. The present results suggest that the enhancing effect of d-amphetamine as demonstrated on Sidman avoidance responding in rats is dependent on the drug experience of the experimental animals and on the experimental situation to which the animals are exposed during the period of the drug effect.Keywords
This publication has 10 references indexed in Scilit:
- Drug effects on blood pressure and heart rate in unanesthetized animalsFolia Pharmacologica Japonica, 1977
- Effects of Thyroidectomy on Amphetamine-Induced Acceleration of Locomotor Activity in MiceThe Japanese Journal of Pharmacology, 1976
- Prior drug experience and effects of amphetamine on schedule controlled behaviorPharmacology Biochemistry and Behavior, 1973
- Tolerance and cross-tolerance to mescaline and amphetamine as a function of central and peripheral administrationPsychopharmacology, 1972
- Tolerance and cross-tolerance among psychotomimetic drugsPsychopharmacology, 1968
- Behavioral variables affecting the development of amphetamine tolerancePsychopharmacology, 1966
- Drug-Behavior Interaction Affecting Development of Tolerance to D-Amphetamine as Observed in Fixed Ratio Behavior of RatsPsychological Reports, 1965
- SPACED RESPONDING IN MULTIPLE DRL SCHEDULES1Journal of the Experimental Analysis of Behavior, 1962
- TIMING BEHAVIOR DURING PROLONGED TREATMENT WITH dl‐AMPHETAMINE1Journal of the Experimental Analysis of Behavior, 1961
- Avoidance Conditioning with Brief Shock and No Exteroceptive Warning SignalScience, 1953