METABOLIC STUDIES IN RATS UNDER GLUCOSE AND GLYCEROL LOADING

Abstract

In rats 40% glycerol, when added to a standard diet, reduces the food intake and thus prevents weight gain. The s.c. application (40 mg/kg 3 times daily) has no effect. Under pair feeding conditions the O2 consumption, the RQ [respiratory quotient] value and body weight remain unaffected compared to controls receiving glucose. Reduction of body weight induced by glycerol feeding is due to the reduced amount of food intake and not due to any alterations of energy metabolism.