Regional Vasomotor Tone in Normotensive and Hypertensive Dogs

Abstract

A new method for estimating vasomotor tone in a local circulation by means of the asystolic arterial pressure gradient was applied to the renal, femoral, brachial, and mesenteric vascular beds of normal dogs and of dogs made hypertensive by various technics. The splanchnic circulation apparently contributes the greatest proportion of the increase of resistance in anesthetized hypertensive animals. The correlation of vasomotor tone with diastolic pressure was good only in the mesenteric area. Some differences in these four areas were found between renal and neurogenic hypertension.