Terrecyclic acid A, a new antibiotic from Aspergillus terreus. I. Taxonomy, production, and chemical and biological properties.

Abstract
A new antibiotic, terrecyclic acid A was isolated from the culture filtrate of a new isolate of fungus, identified as A. terreus. The fermentation yields reached about 1 g/l of the broth. Chemical and biological characterization of the antibiotic revealed that it was a new sesquiterpene having a wide antimicrobial spectrum and antitumor activity.