Amino Acids: Incorporation into α- and β-Chains of Hemoglobin by Normal and Thalassemic Reticulocytes
- 23 October 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 146 (3643), 530-531
- https://doi.org/10.1126/science.146.3643.530
Abstract
After incubation of reticulocytes with radioactive amino acid, the specific activity of the β-chain of globin from the blood of patients with thalassemia was consistently lower than that of the α-chain. In subjects without this disorder, the specific activity of the β-chain was always equal to or higher than that of the α-chain.Keywords
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