Neuroblastoma: Influence of age at diagnosis, stage, tumor site, and sex on prognosis
- 15 October 1980
- Vol. 46 (8), 1896-1901
- https://doi.org/10.1002/1097-0142(19801015)46:8<1896::aid-cncr2820460833>3.0.co;2-y
Abstract
A study of a consecutive series of 99 children with neuroblastoma seen at two major Toronto hospitals between 1951 and 1971 is reported. The children who were aged 24 months or less at diagnosis showed an overall two-year survival rate of 59 percent. Analysis, including fitting of a log-linear model, showed that increased probability of survival was associated with younger age at onset, nonadrenal site, and lower staging and that each of these factors acted independently. The sex of the child had no prognostic effect. This study thus extends earlier work by demonstrating the independent prognostic influence of site of tumor. The implications for treatment policy are discussed.This publication has 8 references indexed in Scilit:
- Initial Urinary Catecholamine Metabolite Concentrations and Prognosis in NeuroblastomaPediatrics, 1978
- NeuroblastomaUrologic Clinics of North America, 1977
- Neuroblastoma: Review of the literature and an examination of factors contributing to its enigmatic characterCancer Treatment Reviews, 1976
- Neuroblastoma, Its Natural History and Prognosis: A Study of 487 CasesBMJ, 1974
- The significance of primitive cells in marrow aspirates of children with neuroblastomaCancer, 1973
- Microscopic patterns as a guide to prognosis of neuroblastoma in childhoodCancer, 1972
- A proposed staging for children with neuroblastoma.Children's cancer study group ACancer, 1971
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958