Sutureless Microvascular Anastomoses by a Biodegradable Laser-Activated Solid Protein Solder
- 1 November 1999
- journal article
- research article
- Published by Wolters Kluwer Health in Plastic and Reconstructive Surgery
- Vol. 104 (6), 1726-1731
- https://doi.org/10.1097/00006534-199911000-00017
Abstract
A new sutureless technique to successfully anastomose the abdominal aorta of rats (1.3 mm in diameter) by using a fully biodegradable, laser-activated protein solder is presented. A total of 90 rats were divided into two groups randomly. In group one, the anastomoses were performed by using conventional microsuturing technique, whereas in group two, the anastomoses were performed by using a new laser welding technique. In addition, each of the two groups were divided into five subgroups and evaluated at different follow-up periods (10 minutes, 1 hour, 1 day, 1 week, and 6 weeks). At these intervals, the anastomoses were evaluated for patency and tensile strength. Three anastomoses in each subgroup were processed for light and electron microscopy. All anastomoses were found to be patent. The mean clamp time of the anastomoses performed with conventional suturing was 20.6 minutes compared with 7.2 minutes for the laser-activated welded anastomoses (p Plast. Reconstr. Surg.Keywords
This publication has 21 references indexed in Scilit:
- Laser-activated solid protein bands for peripheral nerve repair: An in vivo studyLasers in Surgery and Medicine, 1997
- Feasibility studies for laser solder neurorrhaphyPublished by SPIE-Intl Soc Optical Eng ,1994
- CO2 Laser nerve welding: Optimal laser parameters and the use of solders in vitroMicrosurgery, 1994
- Contact diode laser microvascular anastomosisThe Laryngoscope, 1993
- Experimental Diode Laser-Assisted Microvascular AnastomosisJournal of Reconstructive Microsurgery, 1993
- Laser and suture anastomosis: Passive compliance and active force productionLasers in Surgery and Medicine, 1992
- Determination of protein in human serum by high-performance liquid chromatography with semiconductor laser fluorometric detectionAnalytical Chemistry, 1986
- The Normal Healing Process of Microvascular AnastomosesScandinavian Journal of Plastic and Reconstructive Surgery, 1981
- THE HISTOPATHOLOGY OF SMALL ARTERIES FOLLOWING EXPERIMENTAL MICROVASCULAR ANASTOMOSISPlastic and Reconstructive Surgery, 1977
- A SCANNING ELECTRON MICROSCOPE STUDY OF MICROVASCULAR ANASTOMOSESPlastic and Reconstructive Surgery, 1976