Chromosome instability related to gene suppression in Aspergillus nidulans

Abstract

A complicated system of chromosome instability related to gene suppression has been analysed. In addition, unstable genetic events analogous to those previously described in A. nidulans and in other organisms have been detected and one type of unstable variant recovered may be determined by V-type position effect. Furthermore, the selective systems used, clearly offer scope for analysis of genetic instability in general.