RNA sequencing shows no dosage compensation of the active X-chromosome
- 21 November 2010
- journal article
- Published by Springer Science and Business Media LLC in Nature Genetics
- Vol. 42 (12), 1043-1047
- https://doi.org/10.1038/ng.711
Abstract
Jianzhi Zhang and Xionglei He report analyses of published RNA sequencing data examining relative expression levels between genes located on the X chromosome and genes located on autosomes. Unlike previous reports of dosage compensation between the X chromosome and autosomes, their analyses detect an X:autosome expression ratio of [sim]0.5.Keywords
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