A short synthesis of enantiomerically pure (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoic acid, the unusual C9 amino acid found in the immunosuppressive peptide cyclosporine
- 1 June 1987
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 52 (13), 2881-2886
- https://doi.org/10.1021/jo00389a041
Abstract
No abstract availableKeywords
This publication has 5 references indexed in Scilit:
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- Synthesis and antimitogenic activities of four analogs of cyclosporin A modified in the 1-positionJournal of Medicinal Chemistry, 1986
- General method of diastereo- and enantioselective synthesis of β-hydroxy-α-amino acids by condensation of aldehydes and ketones with glycineJournal of the American Chemical Society, 1985
- Synthesis of Cyclosporine. I. Synthesis of enantiomerically pure (2S,3R,4R,6E)‐3‐hydroxy ‐4‐methyl‐2‐methylamino‐6‐octenoic acid starting from tartaric acidHelvetica Chimica Acta, 1983