THE ABSORPTION OF GLUCOSE FROM THE INTESTINE

Abstract

From experiments on an isolated jejunal loop of the unanesthetized dog the authors conclude that the rate of absorption of glucose from the intestinal loop bears a definite relationship to the concentration and the volume of the glucose solution introduced. When the volume and the time are constant, increasing concentrations result in an increasing absorption of glucose. When the volumes introduced are constant there is a definite approximation to a linear relationship between the amount of glucose absorbed and the concentration of the solution. The difference in absorption of glucose from the isolated loop and from the intestine in an intact animal (Cori) may be accounted for by the fact that when glucose solutions of higher concentrations are introduced into the stomach there is dilution of these solutions before they reach the small intestine.