Sequential Activation of Protein Kinase C (PKC)-α and PKC-ε Contributes to Sustained Raf/ERK1/2 Activation in Endothelial Cells under Mechanical Strain
Open Access
- 1 August 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (33), 31368-31375
- https://doi.org/10.1074/jbc.m011317200
Abstract
No abstract availableKeywords
This publication has 45 references indexed in Scilit:
- Nuclear Diacylglycerol Produced by Phosphoinositide-specific Phospholipase C Is Responsible for Nuclear Translocation of Protein Kinase C-αJournal of Biological Chemistry, 1998
- Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway.Journal of Clinical Investigation, 1998
- Effects of Mechanical Forces on Signal Transduction and Gene Expression in Endothelial CellsHypertension, 1998
- Protein Kinase C-ζ Mediates Angiotensin II Activation of ERK1/2 in Vascular Smooth Muscle CellsPublished by Elsevier ,1997
- Strain activation of bovine aortic smooth muscle cell proliferation and alignment: Study of strain dependency and the role of protein kinase A and C signaling pathwaysJournal of Cellular Physiology, 1997
- Translocation Inhibitors Define Specificity of Protein Kinase C Isoenzymes in Pancreatic β-CellsPublished by Elsevier ,1997
- Mitogen-activated protein kinase (ERK1/2) activation by shear stress and adhesion in endothelial cells. Essential role for a herbimycin-sensitive kinase.Journal of Clinical Investigation, 1996
- Cyclic Strain Enhances Adhesion of Monocytes to Endothelial Cells by Increasing Intercellular Adhesion Molecule-1 ExpressionHypertension, 1996
- Protein kinases as mediators of fluid shear stress stimulated signal transduction in endothelial cells: A hypothesis for calcium-dependent and calcium-independent events activated by flowJournal of Biomechanics, 1995
- Strain profiles for circular cell culture plates containing flexible surfaces employed to mechanically deform cells in vitroJournal of Biomechanics, 1994