Metabolism of normal and tumour tissue

Abstract

Medulla of kidney like the retina provides an example of a normal "resting" tissue with an anaerobic type of metabolism. The high anaerobic glycolysis is not abolished under aerobic conditions; glycolysis remains at a high level even when the measurement is made in serum of the same species. Like other normal highly glycolysing tissues, medulla of kidney has a R.Q. near unity. The appearance of aerobic glycolysis may be an expression of energy requirements in excess of blood (i.e., oxygen-) supply.