STUDIES ON LIPID METABOLISM IN THE SMALL INTESTINE WITH OBSERVATIONS ON THE ROLE OF BILE SALTS*†
Open Access
- 1 May 1960
- journal article
- research article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 39 (5), 730-740
- https://doi.org/10.1172/jci104090
Abstract
The esterifi-cation of palmitate-1-C14 and the incorporation of label from glu-cose-C14 into lipid has been studied in slices and everted sacs of mammalian intestine. Palmitate-1-C14 esterification is enhanced by conjugated bile salts which seem to act by affecting the mucosal cell directly. Free bile salts, such as desoxycholate inhibit transport processes and exert a deleterious effect upon the mucous cell causing histological damage.Keywords
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