Functional properties of auditory-nerve fibers during postnatal development in the kitten
- 1 October 1984
- journal article
- research article
- Published by Springer Nature in Experimental Brain Research
- Vol. 56 (3), 395-402
- https://doi.org/10.1007/bf00237980
Abstract
The discharges of the auditory-nerve fibers were studied in kittens between 2–40 days of age. Up to the 10th postnatal day, fibers could be divided into two main categories: (1) fibers with spontaneous activity (SA) that respond to sound and (2) fibers without SA but with evoked responses. A third, smaller, category, fibers having neither SA nor evoked activity, was also present. The development of SA comprises two phases. The first, lasting from birth up to the third postnatal week, shows a relatively fast increase and the second, lasting up to adulthood, a slower increase. Typical tone burst responses can be recorded at the end of the first postnatal week. Thereafter reactivity steadily increases especially after the 10th postnatal day. In young animals, rate level function is characterized by a steep segment with a low dynamic range followed by a decrease in activity that lasts until the end of the second week. At this point adult-like functions may be observed, although maximal firing still increases for some weeks. Tuning curves and threshold sensitivity tend to develop inversely at corresponding frequencies. Fibers with low characteristic frequencies reach adult threshold before that of high frequency fibers and high frequency fibers reach adult tuning before low frequency fibers. A comparison of auditory-nerve fiber activity in kittens show that maturation of most functional characteristics lasts several weeks after birth and in some cases continues after the first postnatal month.Keywords
This publication has 32 references indexed in Scilit:
- Electrophysiological study of the maturation of auditory responses from the inner ear of the chickBrain Research, 1981
- Development of the cat peripheral auditory system: input-output functions of cochlear potentialsBrain Research, 1981
- Age-related changes in the C57BL/6J mouse cochlea. II. Ultrastructural findingsDevelopmental Brain Research, 1981
- Age-related changes in the C57BL/6J mouse cochlea. I. Physiological findingsDevelopmental Brain Research, 1981
- Different patterns of cochlear innervation during the development of the kittenJournal of Comparative Neurology, 1978
- Maturation of function in the developing rabbit retinaJournal of Comparative Neurology, 1977
- Rate versus level functions for auditory-nerve fibers in cats: tone-burst stimuliThe Journal of the Acoustical Society of America, 1974
- The development of unit activity in the lateral geniculate nucleus of the kittenExperimental Neurology, 1974
- Latency of Whole-Nerve Action Potentials: Influence of Hair-Cell NormalcyThe Journal of the Acoustical Society of America, 1972
- Changes in Membrane Properties of Chick Embryonic Hearts during DevelopmentThe Journal of general physiology, 1972