Relationship of pressure to blood flow in the dog kidney

Abstract

Perfusion of the dog kidney via the aorta with no interruption of renal blood flow or disturbance of the kidney or its immediate physical surroundings revealed perfusion pressure-blood flow relationships similar to those previously reported for semi-isolated and isolated kidneys. This suggests that the kidney in the completely intact animal has a local mechanism for holding its blood flow constant despite changes of arterial pressure over the approximate range 70–200 mm Hg.