Uremia

Abstract
THIS review will deal primarily with progress in our knowledge of the pathophysiology of the uremic syndrome. It will touch only briefly the background on which this progress has been made, and the comments on therapy will be limited to the newer aspects of uremia to which they are pertinent. Background material is available in previously published reviews.1 2 3 4 5 Renal Function in UremiaAn explanation for the abnormalities in renal function and the composition of the urine that occur with marked loss of functioning renal tissue was first proposed more than 15 years ago, when it was suggested that the few . . .