Antibody response in pig nasal fluid and serum following foot-and-mouth disease infection or vaccination
- 1 August 1983
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 91 (2), 329-334
- https://doi.org/10.1017/s0022172400060344
Abstract
Nasal fluid and serum collected from pigs after exposure to live foot and mouth disease (FMD) virus or injection of single oil emulsion (w/o) or double oil emulsion (w/o/w) vaccines were examined for FMD neutralizing activity. After virus exposure the response profiles of serum and nasal mucus were similar to one another. In both, neutralizing activity rose to a peak at one to two weeks after exposure and then subsided slowly. After vaccination with either the w/o or w/o/w preparations a neutralizing response was demonstrable in the serum three to seven days after the first injection, and this was boosted by revaccinations 56 and 117 days later. The neutralizing activity was also detectable in nasal fluid seven days after the first vaccination, but subsequent revaccinations 56 and 117 days later provoked neutralizing titres which were no greater than those observed after the initial vaccination.This publication has 14 references indexed in Scilit:
- Antibody response of pigs to foot-and-mouth disease oil emulsion vaccine: the antibody classes involvedResearch in Veterinary Science, 1982
- Immune response to virus-infection-associated (VIA) antigen in cattle repeatedly vaccinated with foot-and-mouth disease virus inactivated by formalin or acetylethyleneimineEpidemiology and Infection, 1979
- A method for the collection of nasal epithelial cells and secretion from domestic animalsVeterinary Record, 1977
- Radial immuno-diffusion and serum-neutralisation techniques for the assay of antibodies to swine vesicular diseaseResearch in Veterinary Science, 1976
- Neutralizing activity in the serum and oesophageal-pharyngeal fluid of cattle after exposure to foot-and-mouth disease virus and subsequent re-exposureArchiv für die gesamte Virusforschung, 1974
- Neutralizing antibody response in bovine serum and nasal and salivary secretions after immunization with live or inactivated food-and-mouth disease virus.1973
- Experiments on vaccination of pigs with ethyl-ethyleneimine (EEI) diethylaminoethyl dextran (DEAE-D) foot-and-mouth disease vaccinesArchiv für die gesamte Virusforschung, 1972
- Versuche zur Schutzimpfung von Schweinen mit Vakzinen aus inaktiviertem Maul- und Klauenseuche (MKS)-VirusArchiv für die gesamte Virusforschung, 1970
- Factors affecting the production of foot-and-mouth disease virus in deep suspension cultures of BHK21 Clone 13 cellsEpidemiology and Infection, 1967
- Secretion of foot-and-mouth disease virus and antibody in the saliva of infected and immunized cattleJournal of Comparative Pathology, 1965