The preparation and properties of ribonucleic acids from rat liver

Abstract
A method of preparation of RNA from rat liver is described involving heat denaturation and separation of the protein and lipid components. It was also applied to cytoplasmic fractions. The yield is, in general, not greater than 50%. The ribonucleic acids obtained have molecular weights between 10,000 and 30,000. The composition of the RNA obtained from the microsome fraction differs appreciably from that obtained by the sodium dodecyl sulfate method.