Effects of phenytoin on schedule-controlled performance of rats
- 1 January 1982
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 78 (1), 93-95
- https://doi.org/10.1007/bf00470597
Abstract
The present study examined the effects of acute administrations of phenytoin on the lever pressing of rats maintained under fixed-ratio, fixed-interval, and interresponse-time-greater-than-T schedules of food delivery. The drug typically produced dose-dependent decreases in response rates under fixed-ratio and fixed-interval schedules, while response rates under the interresponse-time-greater-than-T schedule were affected little by the drug. These findings indicate that phenytoin effects on schedulecontrolled responding differ from those of other anticonvulsants.Keywords
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