ΔFosB: a molecular switch underlying long-term neural plasticity
- 1 December 2000
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Neurology
- Vol. 13 (6), 715-720
- https://doi.org/10.1097/00019052-200012000-00017
Abstract
Numerous chronic perturbations have been shown to induce highly stable isoforms of the transcription factor deltaFosB in the brain in a region-specific manner. This review examines the functional consequences of the induction of deltaFosB in particular neuronal populations as well as its possible role in behavioral abnormalities such as drug addiction and movement disorders.Keywords
This publication has 50 references indexed in Scilit:
- Striatal fosB Expression Is Causally Linked with l-DOPA-Induced Abnormal Involuntary Movements and the Associated Upregulation of Striatal Prodynorphin mRNA in a Rat Model of Parkinson's DiseaseNeurobiology of Disease, 1999
- A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4–CD8– to CD4+CD8+ thymocytesInternational Immunology, 1999
- Selective Effects of Alcohol Drinking on Restraint‐Induced Expression of Immediate Early Genes in Mouse BrainAlcohol, Clinical and Experimental Research, 1999
- Inhibition of p38 MAP kinase increases okadaic acid mediated AP-1 expression and DNA binding but has no effect on TRE dependent transcriptionOncogene, 1999
- Conversion of HPV 18 positive non-tumorigenic HeLa-fibroblast hybrids to invasive growth involves loss of TNF-α mediated repression of viral transcription and modification of the AP-1 transcription complexOncogene, 1999
- Specific regulation of Fos family transcription factors in thymocytes at two developmental checkpointsInternational Immunology, 1999
- Control of the Tissue Inhibitor of Metalloproteinases–1 Promoter in Culture–Activated Rat Hepatic Stellate Cells: Regulation by Activator Protein–1 Dna Binding ProteinsHepatology, 1999
- Transformation by ras modifies AP1 composition and activityOncogene, 1997
- Atypical and typical neuroleptic treatments induce distinct programs of transcription factor expression in the striatumJournal of Comparative Neurology, 1996
- The functional anatomy of basal ganglia disordersTrends in Neurosciences, 1989