Increased tumour extracellular pH induced by Bafilomycin A1 inhibits tumour growth and mitosis in vivo and alters 5-fluorouracil pharmacokinetics
- 1 March 2003
- journal article
- Published by Elsevier in European Journal Of Cancer
- Vol. 39 (4), 532-540
- https://doi.org/10.1016/s0959-8049(02)00671-8
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Four deaths and a funeral: from caspases to alternative mechanismsNature Reviews Molecular Cell Biology, 2001
- Bromocriptine-induced apoptosis in pituitary adenoma cells: relationship to p53 and bcl-2 expressionJournal of Clinical Neuroscience, 1999
- pH and drug resistance. I. functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell linesBiochemical Pharmacology, 1999
- 5-(5,6-Dichloro-2-indolyl)-2-methoxy-2,4-pentadienamides: Novel and Selective Inhibitors of the Vacuolar H+-ATPase of Osteoclasts with Bone Antiresorptive ActivityJournal of Medicinal Chemistry, 1998
- Bafilomycin A1 induces apoptosis in PC12 cells independently of intracellular pHFEBS Letters, 1996
- Acidic pH enhances the invasive behavior of human melanoma cellsClinical & Experimental Metastasis, 1996
- Specific Inhibitors of Vacuolar Type H+-ATPases Induce Apoptotic Cell DeathBiochemical and Biophysical Research Communications, 1995
- Inhibitors of vacuolar‐type H+‐ATPase suppresses proliferation of cultured cellsJournal of Cellular Physiology, 1993
- Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell LinesJNCI Journal of the National Cancer Institute, 1991
- The structure of the bafilomycins, a new group of macrolide antibioticsTetrahedron Letters, 1983