Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
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- 17 September 2001
- journal article
- Published by Springer Nature in The EMBO Journal
- Vol. 20 (18), 5197-5206
- https://doi.org/10.1093/emboj/20.18.5197
Abstract
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.Keywords
This publication has 36 references indexed in Scilit:
- Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau proteinNature Cell Biology, 2000
- Mammalian Oxygen Sensing, Signalling and Gene RegulationJournal of Experimental Biology, 2000
- Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutationsProceedings of the National Academy of Sciences, 2000
- Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1αGenes & Development, 2000
- p42/p44 Mitogen-activated Protein Kinases Phosphorylate Hypoxia-inducible Factor 1α (HIF-1α) and Enhance the Transcriptional Activity of HIF-1Journal of Biological Chemistry, 1999
- Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor FunctionScience, 1999
- Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesisTrends in Genetics, 1998
- Selection and Analysis of a Mutant Cell Line Defective in the Hypoxia-inducible Factor-1 α-Subunit (HIF-1α)Journal of Biological Chemistry, 1998
- Prolyl 4-hydroxylases and their protein disulfide isomerase subunitMatrix Biology, 1998
- Transactivation and Inhibitory Domains of Hypoxia-inducible Factor 1αJournal of Biological Chemistry, 1997