Diuretic treatment and serum lipoproteins: Effects of tienilic acid and indapamide
- 1 April 1981
- journal article
- research article
- Published by Springer Nature in Klinische Wochenschrift
- Vol. 59 (7), 343-346
- https://doi.org/10.1007/bf01525002
Abstract
Summary Treatment with the commonly used diuretic, chlorthalidone, has previously been found to increase the serum low-density-lipoprotein cholesterol (LDL-C) fraction. Therefore, the effects of two new agents, tienilic acid (a combined diuretic-uricosuric) and indapamide on serum lipid and lipoprotein levels were assessed. Six weeks of treatment with tienilic acid, 250 mg/day, markedly decreased serum uric acid and significantly increased LDL-C and triglycerides in 16 men. In contrast, indapamide 2.5 mg/day, had no apparent influence on serum lipids or lipoproteins in 18 men.Keywords
This publication has 14 references indexed in Scilit:
- Increased serum low-density lipoprotein cholesterol in men treated short-term with the diuretic chlorthalidoneMetabolism, 1980
- Ticrynafen: A New Thiazide-Like but Uricosuric Antihypertensive DiureticNew England Journal of Medicine, 1979
- Renal Sites of Natriuretic and Uricosuric Activity of Ticrynafen in the Mongrel DogNephron, 1979
- Ticrynafen: a novel uricosuric antihypertensive natriuretic agentArchives of Internal Medicine, 1978
- Selective Deficiency of Hepatic Triglyceride Lipase in Uremic PatientsNew England Journal of Medicine, 1977
- CHLORTHALIDONE AND SERUM CHOLESTEROLThe Lancet, 1977
- HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study.Circulation, 1977
- Elevation of serum lipid levels during diuretic therapy of hypertensionThe American Journal of Medicine, 1976
- Coronary Artery Disease in 116 Kindred with Familial Type II HyperlipoproteinemiaCirculation, 1974
- Immunochemical quantitation of antigens by single radial immunodiffusionImmunochemistry, 1965