Epithelial Migration On The Tympanic Membrane: An Experimental Study
- 1 January 1978
- journal article
- research article
- Published by Taylor & Francis in Acta Oto-Laryngologica
- Vol. 85 (1-6), 248-252
- https://doi.org/10.3109/00016487809121447
Abstract
The existence of an epidermal migration pattern was studied in mice using a whole-mount autoradio-graphical technique. The mitotic activity appeared to be confined to an area close to the annulus tympanicus. A very slow migratory activity of the labelled cells, was observed, situated in the basal cell layer. Perforation of the tympanic membrane showed no effect on the position of the labelled cells. This slow migration was considered to differ from the rapid epithelial migration described by several authors. The latter migration was suggested to represent a mechanism for cleaning the tympanic membrane.Keywords
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