Binding MOAD, a high-quality protein ligand database
Open Access
- 30 November 2007
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 36 (Database), D674-D678
- https://doi.org/10.1093/nar/gkm911
Abstract
Binding MOAD (Mother of All Databases) is a database of 9836 protein–ligand crystal structures. All biologically relevant ligands are annotated, and experimental binding-affinity data is reported when available. Binding MOAD has almost doubled in size since it was originally introduced in 2004, demonstrating steady growth with each annual update. Several technologies, such as natural language processing, help drive this constant expansion. Along with increasing data, Binding MOAD has improved usability. The website now showcases a faster, more featured viewer to examine the protein–ligand structures. Ligands have additional chemical data, allowing for cheminformatics mining. Lastly, logins are no longer necessary, and Binding MOAD is freely available to all at http://www.BindingMOAD.org .Keywords
This publication has 20 references indexed in Scilit:
- BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinitiesNucleic Acids Research, 2006
- Binding MOAD (Mother Of All Databases)Proteins-Structure Function and Bioinformatics, 2005
- The PDBbind Database: Methodologies and UpdatesJournal of Medicinal Chemistry, 2005
- Development of KiBank, a database supporting structure-based drug designComputational Biology and Chemistry, 2004
- MSDsite: A database search and retrieval system for the analysis and viewing of bound ligands and active sitesProteins-Structure Function and Bioinformatics, 2004
- PDBLIG: Classification of Small Molecular Protein Binding in the Protein Data BankJournal of Medicinal Chemistry, 2004
- Ligand Depot: a data warehouse for ligands bound to macromoleculesBioinformatics, 2004
- Protein Ligand Database (PLD): additional understanding of the nature and specificity of protein–ligand complexesBioinformatics, 2003
- Ligand−Protein DataBase: Linking Protein−Ligand Complex Structures to Binding DataJournal of Medicinal Chemistry, 2001
- The Protein Data BankNucleic Acids Research, 2000