Experimental and theoretical description of the isotachophoretic behavior of serum albumin
- 1 January 1990
- journal article
- research article
- Published by Wiley in Electrophoresis
- Vol. 11 (4), 292-298
- https://doi.org/10.1002/elps.1150110404
Abstract
The isotachophoretic behavior of serum albumin is examined for three anionic and one cationic electrolyte systems by (i) computer simulation, (ii) capillary isotachophoresis (ITP) and (iii) continuous flow ITP. The theoretical relationship between pH of the leading electrolyte and the steady state protein plateau concentration is presented for one of the anionic systems. With leading ion concentrations of the order of 10 mm, experimental protein plateau concentrations of 1.3–2.3 % w/v are obtained. The computer predictions are approximately half these values.This publication has 10 references indexed in Scilit:
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