Progesterone: Its Possible Role in the Biosynthesis of Cardenolides in Digitalis lanata
- 28 April 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 156 (3774), 519-520
- https://doi.org/10.1126/science.156.3774.519
Abstract
The incorporation of progestrone-7α-3H and pregnenolone-7α-3H into digitoxigenin, gitoxigenin, and digoxigenin in isolated, surviving leaves of Digitalis lanata was demonstrated. In addition, the conversion of pregnenolone to progesterone in the same system was proved. The results tend to indicate that progesterone is as good a precursor of cardenolides as pregnenolone It is suggested that the biosynthesis of cardenolides might proceed through the intermediacy of progesterone.This publication has 14 references indexed in Scilit:
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