Nonenzymatic Chloramphenicol Resistance Mediated by IncC Plasmid R55 Is Encoded by a floR Gene Variant
Open Access
- 1 August 2001
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 45 (8), 2381-2382
- https://doi.org/10.1128/aac.45.8.2381-2382.2001
Abstract
The IncC plasmid R55, initially described in the 1970s and isolated from Klebsiella pneumoniae, confers nonenzymatic chloramphenicol resistance. The gene coding for this resistance was cloned and sequenced and shows 95 to 97% nucleotide identity with the recently reported floR gene from Salmonella enterica serovar Typhimurium DT104 and from Escherichia coli animal isolates, respectively, conferring cross-resistance to florfenicol.Keywords
This publication has 14 references indexed in Scilit:
- Plasmid-Mediated Florfenicol Resistance Encoded by the floR Gene in Escherichia coli Isolated from CattleAntimicrobial Agents and Chemotherapy, 2000
- Occurrence of a Salmonella enterica Serovar Typhimurium DT104-Like Antibiotic Resistance Gene Cluster Including the floR Gene in S. enterica Serovar AgonaAntimicrobial Agents and Chemotherapy, 2000
- Detection of Florfenicol Resistance Genes in Escherichia coli Isolated from Sick ChickensAntimicrobial Agents and Chemotherapy, 2000
- Evolution of chloramphenicol resistance, with emergence of cross-resistance to florfenicol, in bovine Salmonella Typhimurium strains implicates definitive phage type (DT) 104Journal of Medical Microbiology, 2000
- A new chloramphenicol and florfenicol resistance gene flanked by two integron structures inSalmonella typhimuriumDT104FEMS Microbiology Letters, 1999
- Sequence Analysis of the Florfenicol Resistance Gene Encoded in the Transferable R‐Plasmid of a Fish Pathogen, Pasteurella piscicidaMicrobiology and Immunology, 1996
- A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivativesJournal of Antimicrobial Chemotherapy, 1990
- Nucleotide sequence of the R26 chloramphenicol resistance determinant and identification of its gene productGene, 1986
- Chloramphenicol Resistance that does not Involve Chloramphenicol Acetyltransferase Encoded by Plasmids from Gram-negative BacteriaMicrobiology, 1981
- Chloramphenicol Acetyltransferases Determined by R Plasmids from Gram-negative BacteriaJournal of General Microbiology, 1978