Dopamine D2 receptor alteration in patients with periodic movements in sleep (nocturnal myoclonus)
- 1 February 1993
- journal article
- research article
- Published by Springer Nature in Journal of Neural Transmission
- Vol. 93 (1), 71-74
- https://doi.org/10.1007/bf01244940
Abstract
Periodic movements in sleep (PMS) can cause severe sleep disturbances. We investigated the central dopamine D2 receptor density in patients with PMS with123I-IBZM and single photon emission tomography (SPET). In PMS there was a lower123I-IBZMbinding in the basal ganglia compared tothe control group. The results indicate a loss of central D2 receptors in PMS.Keywords
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