Extensive Use of a Diagnostic Test for Meniere Disease

Abstract

The glycerin test for endolymphatic hydrops was administered to 122 patients with sensorineural hearing loss and a potential diagnosis of Meniere disease. Significant improvement for sensitivity and/or speech discrimination ability was shown at a three-hour period following ingestion of glycerin for 50 of the 97 ears with the final diagnoses of Meniere disease. Only one false-positive finding was observed among the 59 ears in other final diagnostic categories. Cases of acoustic neuroma gave negative glycerin responses. Procedures and side effects of the test are acceptable for office practice.