The Complete Amino Acid Sequence of Human P2 Protein
- 1 December 1982
- journal article
- Published by Wiley in Journal of Neurochemistry
- Vol. 39 (6), 1759-1762
- https://doi.org/10.1111/j.1471-4159.1982.tb08017.x
Abstract
The complete amino acid sequence of P2 protein from human peripheral nerve myelin was determined from nine staphylococcal protease peptides and four cyanogen bromide peptides. Human P2 protein is composed of 131 amino acids and has a molecular weight of 14,818. Compared to bovine P2 protein, there are replacements at nine positions (human↔bovine): 18(Asp↔Glu), 39(Thr↔Arg), 56(Thr↔Pro), 83(Ile↔Thr), 87(Gln↔Ala), 96(Arg↔Lys), 100(Lys↔Asn), 115 (Ala↔Val), and 121(Gly↔Asp).Keywords
This publication has 17 references indexed in Scilit:
- Neuritogenic Determinant of Bovine P2 Protein in Peripheral Nerve MyelinJournal of Neurochemistry, 1982
- The neuritogenicity and encephalitogenicity of P2 in the rat, guinea-pig and rabbitJournal of the Neurological Sciences, 1980
- Neuritogenic activity of peripheral nerve myelin proteins in Lewis ratsNeuroscience Letters, 1980
- Experimental allergic neuritis. I. Rat strain differences in the response to bovine myelin antigensBrain Research, 1980
- The complete amino acid sequence of the P2 protein in bovine peripheral nerve myelinFEBS Letters, 1980
- Identification of the neuritogen for experimental allergic neuritisNature, 1979
- The Amino‐Acid Sequence of S‐100 Protein (PAP I‐b Protein) and Its Relation to the Calcium‐Binding ProteinsEuropean Journal of Biochemistry, 1978
- Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and SacBiochemistry, 1971
- ALLERGIC NEURITIS: AN EXPERIMENTAL DISEASE OF RABBITS INDUCED BY THE INJECTION OF PERIPHERAL NERVOUS TISSUE AND ADJUVANTSThe Journal of Experimental Medicine, 1955
- Colour Reactions on Paper Chromatograms by a Dipping TechniqueNature, 1953