Human type II collagen gene (COL2A1) assigned to chromosome 12q13.1-q13.2 byin situ hybridization with biotinylated DNA probe
- 1 December 1989
- journal article
- research article
- Published by Springer Nature in Journal of Human Genetics
- Vol. 34 (4), 307-311
- https://doi.org/10.1007/bf01929213
Abstract
Summary We have made a regional assignment of the type II collagen gene (COL2A1) on human chromosome 12 by means of anin situ hybridization technique with a biotinylated DNA probe. The precise localization of the signal was mapped to the band 12q13.1-q13.2. This result was in agreement with the previous mapping by isotopicin situ hybridization technique (12q13.1-q13.2), but not with the result of Southern hybridization analysis using somatic cell hybrids (12q14.3).Keywords
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