Human leukemic “null” cell line (NALL-1)
Open Access
- 1 November 1977
- Vol. 40 (5), 2131-2135
- https://doi.org/10.1002/1097-0142(197711)40:5<2131::aid-cncr2820400523>3.0.co;2-v
Abstract
A human lymphoblast cell line, NALL‐1, was established from the peripheral blood of a patient with acute lymphoblastic leukemia (ALL). NALL‐1 cells had neither properties of T and B cells nor Epstein‐Barr virus (EBV). Many characteristics of the NALL‐1 line were distinct from those of numerous EBV‐positive lymphoblastoid cell lines previously reported. NALL‐1 cells are considered to have originated from the donor's leukemic cells on the basis of their cytogenetic, morphologic and functional features. The NALL‐1 line is the first human leukemic “null” cell line derived from ALL. The significance of this cell line is discussed.This publication has 20 references indexed in Scilit:
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