The effect of age on the fibrinolytic enzyme system
- 1 April 1974
- journal article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 27 (4), 326-329
- https://doi.org/10.1136/jcp.27.4.326
Abstract
Components of the fibrinolytic enzyme system, FR-antigen and fibrinogen, were measured in 20 healthy volunteers aged 20-40 years and in 61 elderly subjects aged 66-96 years. Plasminogen activator levels did not significantly differ between the 20-40 and 66-75 age groups, but were higher in those over 75. Plasminogen showed no change with age except for a fall in those over 75. Fibrinogen, FR-antigen, α1-antitrypsin, and α2-macroglobulin all rose with age, but the mean fibrinogen concentration fell in the very elderly.Keywords
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