Pharmahuasca: Human Pharmacology of Oral DMT Plus Harmine
- 1 April 1999
- journal article
- review article
- Published by Taylor & Francis in Journal of Psychoactive Drugs
- Vol. 31 (2), 171-177
- https://doi.org/10.1080/02791072.1999.10471741
Abstract
A summary is presented of human self-experiments or psychonautic bioassays of pharmahuasca—capsules containing crystalline N,N-dimethyltryptamine (DMT) plus harmine, as well as combinations of other psychoactive tryptamines with other β-carbolines. The 1967 Holmstedt–Lindgren hypothesis of the ayahuasca effect—oral psychoactivity of DMT consequent to monoamine-oxidase (MAO) inhibition from simultaneous ingestion of β-carbolines—has been confirmed by eight self-experimenters. Results of a total of some 70 bioassays are summarized and the literature on this subject is reviewed (with 66 references and one table).Keywords
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