Effect of zotepine on head-twitch induced by L-5-Hydroxytryptophan,mescaline and 2,5-Dimethoxy-4-methylamphetamine in mice and rats.
- 1 January 1983
- journal article
- research article
- Published by Elsevier in The Japanese Journal of Pharmacology
- Vol. 33 (2), 319-325
- https://doi.org/10.1254/jjp.33.319
Abstract
The effect of zotepine, a new neuroleptic, on head-twitch induced by L-5-hydroxytryptophan (L-5HTP), mescaline and 2,5-dimethoxy-4-methylamphetamine (DOM) in mice and rats was compared with that of known neuroleptics and the serotonin receptor blocker cyproheptadine. Among the neuroleptics tested, zotepine and haloperidol produced potent inhibitory effects on head-twitch induced by these 3 drugs. Zotepine evidently has a potent anti-hallucinogenic effect.This publication has 9 references indexed in Scilit:
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