Synthesis of 2-Methylpyrrolo[1,2-a]pyrazin-1(2h)-one
- 1 January 1988
- journal article
- research article
- Published by CSIRO Publishing in Australian Journal of Chemistry
- Vol. 41 (10), 1583-1590
- https://doi.org/10.1071/ch9881583
Abstract
The synthesis of 2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one (2) present in the insect feeding deterrent peramine (1) through oxidation of the saturated lactam (3) is described. The preparation of the related 6- methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one (12) through a Lewis-acid- catalysed cyclization of the amide acetal (7) is also described.Keywords
This publication has 1 reference indexed in Scilit:
- ETHYL PYRROLE-2-CARBOXYLATEOrganic Syntheses, 1971