Antibiotic-induced changes of mycelial growth ofBotrytis cinerea

Abstract

The effect of antibiotics and metabolic inhibitors on mycelial growth ofBotrytis cinerea was followed. Inhibitors of protein synthesis, chloramphenicol, erythromycin and tetracycline inhibit growth or sporulation ofBotrytis cinerea. Ethidium bromide, 5-fluorouracil, phenylethylalcohol and K 20 cause granulation, vacuolization and undulation of hyphae. 2,4-Dinitrophenol, boromycin, macrotetrolides, monensin, scopathricin and TX₂ at subfungistatic concentrations induce intensive branching of hyphal tipsi.e. at the site of synthesis of the cell wall. In older hyphae grown in the absence of the antibiotics the branching begins after their addition, particularly in the septum region. When comparing the results referred to here with those obtained previously and on the basis of literature data it may be assumed that the changes in polarity of growth ofBotrytis cinerea might be caused primarily or secondarily by impairing membrane functions and formation of cell walls.