Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity
Open Access
- 1 September 2006
- journal article
- Published by American Society of Hematology in Blood
- Vol. 108 (5), 1744-1750
- https://doi.org/10.1182/blood-2006-04-016634
Abstract
The prognosis for patients with mantle cell lymphoma (MCL) is poor, and at present there is no truly effective therapy. Gene translocation-mediated constitutiveKeywords
This publication has 35 references indexed in Scilit:
- Mantle Cell LymphomaPublished by Elsevier ,2011
- Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphomaOncogene, 2005
- Rabbit Monoclonal AntibodiesAmerican Journal of Clinical Pathology, 2005
- Rabbit Monoclonal Antibodies: A Comparative Study Between a Novel Category of Immunoreagents and the Corresponding Mouse Monoclonal AntibodiesAmerican Journal of Clinical Pathology, 2005
- Proteomic analysis of mantle-cell lymphoma by protein microarrayBlood, 2005
- The mTOR Inhibitor RAD001 Sensitizes Tumor Cells to DNA-Damaged Induced Apoptosis through Inhibition of p21 TranslationCell, 2005
- Mammalian Cells Cycle without the D-Type Cyclin-Dependent Kinases Cdk4 and Cdk6Cell, 2004
- Mouse Development and Cell Proliferation in the Absence of D-CyclinsCell, 2004
- Cyclin D1 Splice VariantsJournal of Biological Chemistry, 2003
- Inhibition of the proteasome induces cell cycle arrest and apoptosis in mantle cell lymphoma cellsBritish Journal of Haematology, 2003