Pantothenic Acid Studies X. The Influence of a Pantothenic Acid Conjugate (PAC) Upon Growth and Citrate Formation in Rats

Abstract

PAC administered either intraperitoneally or orally was as active as free pantothenic acid in supporting the growth of young albino rats. The liver homogenates of rats grown on a pantothenic acid-deficient diet showed a reduced capacity for the formation of citrate. The livers of PAc-supplemented rats showed the same restoration of this activity as those of animals supplemented with the free vitamin. The degree of difference in the ability to form citrate among the animals receiving graded amounts of pantothenic acid was not as great as the differences in body weight.