Abstract
One S. aureus plasmid coding for tetracycline resistance, pT127, and 4 plasmids (pC194, pC221, pC223 and pUB112) coding for chloramphenicol resistance were introduced by transformation into B. subtilis. The plasmids replicate in.sbd.and confer antibiotic resistance upon.sbd.their new host. These experiments show that the potential for genetic exchange between diverse bacterial species is greater than was commonly assumed. [S. aureus plasmids introduced into B. subtilis are promising vectors for cloning in this new host.].