Enlargement of salivary glands in rats after chronic administration of physalaemin or isoprenaline
- 1 May 1966
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 18 (5), 312-316
- https://doi.org/10.1111/j.2042-7158.1966.tb07877.x
Abstract
Chronic administration of physalaemin and isoprenaline to rats produced a significant salivary glands enlargement which was moderate (34% fresh weight increase and 48% dry weight increase compared with control glands) after the peptide administration and striking after the amine (630% fresh weight increase and 600% dry weight increase compared with control glands). Physalaemin caused only hypertrophy of the gland, whereas isoprenaline induced a marked hyperplasia.This publication has 8 references indexed in Scilit:
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- OCCURRENCE OF PHYSALAEMIN IN EXTRACTS OF THE SKIN OF PHYSALAEMUS FUSCUMACULATUS AND ITS PHARMACOLOGICAL ACTIONS ON EXTRAVASCULAR SMOOTH MUSCLEBritish Journal of Pharmacology and Chemotherapy, 1965
- Structure and pharmacological actions of physalaemin, the main active polypeptide of the skin ofPhysalaemus fuscumaculatusCellular and Molecular Life Sciences, 1964
- Salivary gland changes after isoproterenol-induced enlargementAmerican Journal of Physiology-Legacy Content, 1962
- Submandibular salivary gland weight increase by administration of isoproterenol to ratsAmerican Journal of Physiology-Legacy Content, 1962
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