Out‐and‐in spiral spectroscopic imaging in rat brain at 7 T

Abstract
With standard spectroscopic imaging, high spatial resolution is achieved at the price of a large number of phase‐encoding steps, leading to long acquisition times. Fast spatial encoding methods reduce the minimum total acquisition time. In this article, a k‐space scanning scheme using a continuous series of growing and shrinking, or “out‐and‐in,” spiral trajectories is implemented and the feasibility of spiral spectroscopic imaging for animal models at high B0 field is demonstrated. This method was applied to rat brain at 7 T. With a voxel size of about 8.7 μl (as calculated from the point‐spread function), a 30 × 30 matrix, and a spectral bandwidth of 11 kHz, the minimum scan time was 9 min 20 sec for a signal‐to‐noise ratio of 7.1 measured on the N‐acetylaspartate peak. Magn Reson Med 50:1127–1133, 2003.
Funding Information
  • Bruker (Wissembourg, France)
  • Association pour la Recherche contre le Cancer
  • “Programme Interdisciplinaire Imagerie du Petit Animal” (CNRS - INSERM)