REACTIVITY OF ANTI-STRIATIONAL ANTIBODIES ASSOCIATED WITH THYMOMA AND MYASTHENIA-GRAVIS
- 1 January 1977
- journal article
- research article
- Vol. 27 (1), 66-73
Abstract
Using immunofluorescence, 49 sera [human] giving striational staining of skeletal and cardiac muscle were tested on glycerinated myofibrils. By comparing immunofluorescence and phase contrast it was found that these antibodies are rather heterogeneous, but at least 3 different staining patterns can be identified. Some patterns may be associated with the presence of a thymoma or may be induced by penicillamine treatment of patients with rheumatoid arthritis. Routine screening for antistriational antibodies may lead to the recognition of undiagnosed myasthenia gravis and thymoma.This publication has 14 references indexed in Scilit:
- The Skeletal Muscle Binding Site of Antistriated Muscle Antibody in Myasthenia Gravis: An Electron Microscopic Immunohistochemical Study Using Peroxidase Conjugated Antibody FragmentsThe Journal of Immunology, 1973
- Studies in myasthenia gravis. Heat stability and species specificity of active muscle antigens.1973
- Myasthenia Gravis: Cross-Striational Fluorescence of Muscle Fibers Mediated by Fc FragmentsThe Journal of Immunology, 1972
- Myasthenia gravis. Antibodies to an acid-soluble antigen in striated muscle.1972
- [Autoimmunity in myasthenia and thymoma].1970
- Serum Autoantibodies in Myasthenia Gravis and Thymoma: Selective Affinity for I-Bands of Striated Muscle As a Guide to Identification of Antigen(s)The Journal of Immunology, 1967
- PRECIPITATION OF AUTOANTIBODY IN SERUM FROM PATIENTS WITH MYASTHENIA GRAVIS1966
- FURTHER STUDIES ON THE SPECIFICITY OF PRESUMED IMMUNE ASSOCIATIONS OF MYASTHENIA GRAVIS AND CONSIDERATION OF POSSIBLE PATHOGENIC IMPLICATIONSAnnals of the New York Academy of Sciences, 1966
- SEROLOGIC STUDIES OF MYASTHENIA GRAVIS*Annals of the New York Academy of Sciences, 1965
- Studies on autoantibodies in myasthenia gravis.1962