Genetic Linkage Studies of Transf errin, Pseudocholinesterase, and Chromosome 1 Loci
- 31 December 1983
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 34 (2), 96-100
- https://doi.org/10.1159/000153442
Abstract
Genetic linkage analysis of a pedigree with four different alleles for pseudocholinesterase (CHEl) gives a positive lod score of 0.37 at Θ= 0.16 for linkage with transferrin (TF), a finding which supports previous reports of linkage between CHEl and TF. Evaluation of linkage relations of CHEl and TF using unreported families from our data bank fails to establish linkage with chromosome 1 loci (6-PGD, Rh, PGM1, AMY2 and FY). These results are consistent with recent studies which suggest that TF is on human chromosome 3.Keywords
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- Evidence for linkage between the transferrin locus (Tf) and the serum cholinesterase locus (El) in manAnnals of Human Genetics, 1966