Immunity to the Common Cold from Protective Serum Antibody
- 19 April 1962
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 266 (16), 791-796
- https://doi.org/10.1056/nejm196204192661601
Abstract
UNTIL recently, the information available on immunity to the common cold indicated that little if any immunity developed as a consequence of overt infection. As a result of studies in volunteers, we have presented data showing that common viral respiratory infections both elicit an antibody response and protect the host against infection upon rechallenge.1 The capacity of agents of the common cold to stimulate an antibody response in man was observed in studies showing that pooled human gamma globulin neutralized infectious nasal secretions.2 Critical to the changing concept regarding immunity has been the recognition of strain specificity among the viral . . .Keywords
This publication has 6 references indexed in Scilit:
- SUSCEPTIBILITY AND IMMUNITY TO COMMON UPPER RESPIRATORY VIRAL INFECTIONS—THE COMMON COLDAnnals of Internal Medicine, 1960
- INFECTIVITY AND INTERRELATIONSHIPS OF 2060-VIRUS AND JH-VIRUS IN VOLUNTEERS1960
- TRANSMISSION OF THE COMMON COLD TO VOLUNTEERS UNDER CONTROLLED CONDITIONS. IV. SPECIFIC IMMUNITY TO THE COMMON COLD*JCI Insight, 1959
- Neutralization of Common Cold Agents in Volunteers by Pooled Human GlobulinScience, 1958
- Transmission of the Common Cold to Volunteers Under Controlled ConditionsA.M.A. Archives of Internal Medicine, 1958
- EXPERIMENTAL TRANSMISSION OF MINOR RESPIRATORY ILLNESS TO HUMAN VOLUNTEERS BY FILTER-PASSING AGENTS. II. IMMUNITY ON REINOCULATION WITH AGENTS FROM THE TWO TYPES OF MINOR RESPIRATORY ILLNESS AND FROM PRIMARY ATYPICAL PNEUMONIA 1JCI Insight, 1947