CENTRAL NERVOUS SYSTEM RESISTANCE

Abstract

Animals were subjected to periods of complete arrest of the cerebral circulation of 2, 4, 6, 8 and 10 mins. Susceptibility differences were marked in different areas of the brain and a certain degree of local selectivity and specificity was evident. There appears to be a gradient of resistance, which from the lowest to highest degrees of resistance is as follows cerebral cortex (isocortex), cerebellar cortex (Purkinje cells), sensory and integrative centers of the brain stem, pons and medulla, cerebral cortex (allocortex) and finally, large motor cells of brain stem, pons, medulla, and spinal cord.