Herpes Gestationis
- 1 July 1974
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 110 (1), 65-69
- https://doi.org/10.1001/archderm.1974.01630070033005
Abstract
During the second trimester of pregnancy, a patient developed herpes gestationis characterized by a widespread eruption of iris lesions with peripheral subepidermal vesicles and severe blood eosinophilia. Direct immunofluorescent studies of lesions showed deposition of IgG, C1q, C3, and properdin at the basement membrane, implicating both classic and alternate complement pathway activation. A circulating antibody to basement membrane, previously undescribed, to our knowledge, in this disease, was found, which suggests that herpes gestationis may be related to bullous pemphigoid.Keywords
This publication has 5 references indexed in Scilit:
- Herpes gestationisPublished by Springer Nature ,2011
- Evidence for Complement Activation via the Alternate Pathway in Skin Diseases I HERPES GESTATIONIS, SYSTEMIC LUPUS ERYTHEMATOSUS, AND BULLOUS PEMPHIGOIDJournal of Clinical Investigation, 1973
- Procedures for the Immunization of Goats with Human Immunoglobulins and ComplementInternational Archives of Allergy and Immunology, 1970
- GRANULAR DEPOSITS OF IMMUNOGLOBULINS IN THE SKIN OF PATIENTS WITH DERMATITIS HERPETIFORMIS. AN IMMUNOFLUORESCENT STUDYBritish Journal of Dermatology, 1969
- The Presence of Complement “Bound” in vivo in the Skin of Patients with PemphigoidDermatology, 1968