STUDIES ON THE CORONARY CIRCULATION

Abstract

The intravenous administration of dextrose has become an important therapeutic procedure. The use of dextrose in shock accompanying coronary thrombosis and in other forms of medical shock is now rather widespread. Marvin¹ recently reported that injections of dextrose have been effective in the treatment of heart failure and cardiac disturbances brought about by diphtheria. Edwards and Page² showed that intravenous injections of dextrose produce marked improvement in the action of hypodynamic hearts of dogs suffering from hypoglycemia produced by insulin. Middleton and Oatway³ found that diabetic patients suffering from anginal pains were frequently hypoglycemic or that the sugar level was below that usually found in diabetic patients. Root and Graybiel⁴ reported that in some patients the anginal pains are relieved by the intravenous injection of a solution of dextrose (20 cc. of a 50 per cent solution). Strouse, Soskin, Katz and Rubinfeld⁵ reported that in